Comparative pharmacokinetic analysis of thiamine and its phosphorylated metabolites administered as multivitamin preparations. Recommended Dietary Allowance (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%98%) healthy individuals; often used to plan nutritionally adequate diets for individuals. Pediatr Clin North Am 2009;56:1105-21. Some small studies have shown that oral supplementation with 150300 mg/day thiamin can decrease glucose levels in patients with type 2 diabetes or impaired glucose tolerance [41,42]. Am J Med 1991;91:151-5. Thiamin (or thiamine) is one of the water-soluble B vitamins. Thiamine will be given in the hospital through an IV for severe deficiencies. Thiamine supplementation in symptomatic chronic heart failure: a randomized, double-blind, placebo-controlled, cross-over pilot study. Wernicke encephalopathy after bariatric surgery: a systematic review. In: Erdman JW, Macdonald IA, Zeisel SH, eds. Thiamin: fact sheet for consumers. Vitamin B1 is essential for a healthy nervous system and overall well-being, providing the body nourishment for the occasional stress of daily living. 2017;13:727741. Often, supplements that can be bought over the counter containthiamine mononitrate or thiamine hydrochloride,which are stable forms of thiamine. The result is typically 0%15% in healthy people, 15%25% in those with marginal deficiency, and higher than 25% in people with deficiency. The following products are definitely Halal: Milk (from cows, sheep, camels, and goats) Honey. It plays an important role in many biological processes, mainly in glucose metabolism. No supplement is intended to treat, cure, or prevent disease. They leave the body through the urine. J Alzheimers Dis. When thiamine is given through an IV for seriousdeficiencies, there may be a risk of an allergic reaction, but the benefits would outweigh the risks in these cases. [. This article discusses the potential uses of thiamine. [. In the developed world, a lack of thiamine is more often caused by a disease or condition that is either causing an inability to consume foods with enough thiamine or one that interferes with thiamine absorption. It helps to convert what you eat and drink into energy or glucose. This syndrome is a late stage of thiamine deficiency. A severe deficiency could lead to decreased production of some enzymes and go on to cause problems in brain function. CJC Open. People who live with certain conditions, includingalcohol use disorder, diabetes, certain gastrointestinal conditions or surgeries, or heart failure,may need to watch for thiamine deficiencies. It's used as a co-enzyme in ATP (energy) production. Because thiamin can only be stored in the body for a short time before it is readily excreted, a regular dietary intake of thiamin is necessary to maintain proper blood levels. Rosen A, van Kuilenburg A, Assmann B, Kuhlen M, Borkhardt A. If an ingredient is missing, please use the comment form below to report it and we will look into it. A deficiency of thiamine, or vitamin B1, may go undiagnosed and is associated with poor health outcomes, including death. The review authors stated that it was not possible to draw any conclusions from these three studies because they were small and the publications describing them did not provide enough detail to combine these data in a meta-analysis. Administration of supplemental thiamin, often parenterally, quickly cures beriberi [2,3]. Are these halal or Haram in Medicine, did not find on your list. Age Ageing 1990;19:325-9. Diabetologia 2007;50:2164-70. Among children and teens, the average daily thiamin intake from foods is 1.27 mg for ages 25 years, 1.54 mg for ages 611 years, and 1.68 mg for ages 1219 years [14]. Some available supplements may include one or more synthetic forms of vitamin B1. Amber J. Tresca is a freelance writer and speaker who covers digestive conditions, including IBD. This syndrome is serious and can even be deadly. Baltimore, MD: Lippincott Williams & Wilkins; 2014:317-24. Cochrane Database Syst Rev 2001:CD001498. The authors of a systematic literature review and meta-analysis found two randomized, double-blind, placebo-controlled trials of thiamin supplementation in people with heart failure that met their eligibility criteria [50]. Acta Biomed Ateneo Parmense 1992;63:43-9. However, bariatric surgery (weight-loss surgery that modifies the digestive system) rates increased dramatically from 2006 through 2021, and it is a risk factor for thiamine deficiency. Int J Mol Sci. Solgar Vitamin B-Complex "50" indeholder 50 mg af hvert vitamin B. Riboflavin (Vitamin B2), Niacin (Vitamin B3), Vitamin B6 og B12 bidrager til at reducere trthed og udmattelse. Rates of deficiency were even higher when the investigators excluded those who used thiamin supplements. [. Groups With a Higher Incidence of Thiamine Deficiency. Present Knowledge in Nutrition. 2013;13:495-499. In highly industrialized countries, chronic alcohol use disorders appear to be the most common cause of thiamin deficiency [1]. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Breads, cereals, and infant formulas in the United States and many other countries are fortified with thiamin [2].The most common sources of thiamin in the U.S. diet are cereals and bread [8]. These randomized, double-blind, placebo-controlled trials compared 5 mg/day by mouth for 2 weeks or daily intramuscular doses of 5 to 200 mg/day thiamin over 2 consecutive days in a total of 177 people with a history of chronic alcohol use. J Am Geriatr Soc 2009;57:2166-8. It is also involved in the flow of electrolytes into and out of . Halal is an Arabic word means lawful or permitted. These values, which vary by age and sex, include: Table 1 lists the current RDAs for thiamin [7]. Overview of Wernicke-Korsakoff Syndrome or Alcohol Dementia, The 7 Best B12 Supplements of 2023, According to a Dietitian, Thiamin fact sheet for health professionals, Evaluation of the safety of 500 mg intravenous push thiamine at a tertiary academic medical center, Thiamine for prevention and treatment of Wernicke-Korsakoff syndrome in people who abuse alcohol, Thiamine level in type I and type II diabetes mellitus patients: a comparative study focusing on hematological and biochemical evaluations. O you who have believed, eat from the good things which We have provided for you and be grateful to Allah if it is [indeed] Him that you worship. Surah Baqarah 2:172. Case Rep Oncol 2010;3:362-7. 101,102 Thiaminase I uses nucleophiles such as quinoline, aniline, and pyridine but not water. Also synthetically produced. Although beriberi is rare in the United States and other developed countries, people in these countries do occasionally develop the condition [15-18]. Int Rev Neurobiol. BMC Med. Vitamin B1: As Thiamine (synthetic and from eggs) Said HM. Galvin R, Brathen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA. Pls also merits of islamic month. Sharma S, Sheehy T, Kolonel LN. When possible, choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF. As Muslims, we must have knowledge of halal and haram ingredients in order to eat what is permissible. Does long-term furosemide therapy cause thiamine deficiency in patients with heart failure? These people will also need more intensive therapy to improve their ability to learn and retain memories. [. Vitamin A: If source are plant and synthetic, it is halal. However, the FNB noted that in spite of the lack of reported adverse events, excessive intakes of thiamin could have adverse effects. Parrott J, Frank L, Rabena R, et al. Gibson GE, Luchsinger JA, Cirio R, et al. Thiamine for Alzheimer's disease. Vitamin B1, also called thiamine or thiamin, is one of 8 B vitamins. In a study of 76 consecutive patients with type 1 or type 2 diabetes, for example, 8% had mild thiamin deficiency and 32% had moderate deficiency based on assays of the transketolase enzyme [33]. A more common manifestation of thiamin deficiency in the United States is Wernicke-Korsakoff syndrome [2]. The authors did not assess the clinical significance of this finding, however. [. It's also used in our nervous system to help transmit nerve impulses and some other stuff that's hard to understand without a biochemistry degree! [, Gibson GE, Hirsch JA, Cirio RT, Jordan BD, Fonzetti P, Elder J. Abnormal thiamine-dependent processes in Alzheimer's Disease. Guidelines from the American Society for Metabolic and Bariatric Surgery also recommend that thiamine levels be tested in people who have gastric surgery and are at risk for a thiamine deficiency. Thiamine-dependent processes and treatment strategies in neurodegeneration. Without treatment, up to 20% of people with Wernickes encephalopathy die; those who survive develop Korsakoffs psychosis, although some people with Korsakoffs psychosis have not previously had Wernickes encephalopathy [20,21]. People who arent able to eat enough food with thiamine in it, such as those who are receiving nutritional support because of an illness, may not be getting enough of this vitamin. Ito Y, Yamanaka K, Susaki H, Igata A. J Korean Med Sci 2009;24:747-50. 2019;54:609-614. doi:10.1093/alcalc/agy091, Katta N, Balla S, Alpert MA. However, the authors recommend parenteral thiamin supplementation for patients at high risk, such as those with ataxia, confusion, and a history of chronic alcohol misuse, because oral supplementation is unlikely to produce adequate blood levels. American Society for Metabolic and Bariatric Surgery integrated health nutritional guidelines for the surgical weight loss patient 2016 update: micronutrients. 2020;43:964-973. doi:10.14348/molcells.2020.0198, Allowitz KV, Yoo JJ, Taylor JR, et al. Ochsner J 2013;13:495-9. Thiamine and cardiovascular disease: a literature review. As it in your old islamcan app Vitamin C: Natural sources are from plant. The most common effect of thiamin deficiency is beriberi, which is characterized mainly by peripheral neuropathy and wasting [1-3]. Thiamin supplementation does not improve left ventricular ejection fraction in ambulatory heart failure patients: a randomized controlled trial. At this chronic state of the disorder, parenteral thiamin treatment does not lead to recovery in about one-quarter of patients [22]. -Hydroxypropyl starch phosphate J Am Coll Cardiol 2006;47:354-61. Polegato BF, Pereira AG, Azevedo PS, et al. For a reader-friendly overview of Thiamin, see our consumer fact sheet on Thiamin. The recommended daily intake (RDI) for adults over age eighteen is 1.2 mg/day for men and 1.1 mg/day for women. Whether thiamin supplements are effective for preventing thiamin deficiency in patients taking loop diuretics needs to be determined in clinical studies. Boldorini R, Vago L, Lechi A, Tedeschi F, Trabattoni GR. [1] Only small amounts are stored in the liver, so a daily intake of thiamin-rich foods is needed. They hypothesize that the apparent lack of toxicity may be explained by the rapid decline in absorption of thiamin at intakes above 5 mg. Ann Nutr Metab 2012;61:219-23. American Society for Metabolic and Bariatric Surgery. Thiamin is found in fortified processed flours and ready-to-eat cereals, lean pork, beef, wheat germ and whole grains, yeast, organ meats (especially liver), eggs, fish, legumes, and nuts. Not enough is known about how thiamine supplements may help people with heart failure, and the authors of one meta-analysis are calling for more research. Blood thiamine levels in outpatients with diabetes mellitus. 2021;58(11):1433-1439. doi:10.1007/s00592-021-01752-4, DiNicolantonio JJ, Liu J, O'Keefe JH. We encourage you to talk to your health care providers (doctor, registered dietitian, pharmacist, etc.) Thiamin (Vitamin B1) Thiamin is a nutrient found in Whole grains, rice, meats, eggs, milk, and green-leaf vegetables. 2013;7:CD004033. Thiamine (Vitamin B1), Biotin (Vitamin B7), Niacin (B3) Vitamin B6 bidrager til normal nervesystem . 3 The body uses thiamine to get the energy to grow cells and support body functions. Wernicke's Encephalopathy in Colon Cancer. *DV = Daily Value. They recommend 200 mg thiamin, preferably intravenously, three times daily (total of 600 mg/day) until the signs and symptoms stop, along with a balanced diet. Most people get enough thiamine through their diet. JazakAllah. [. Vitamin D: Natural sources are yeast and fish liver oil. Bemeur C, Butterworth RF. Fish. Estimate of bariatric surgery numbers, 2011-2020. -Styrene/Acrylates Copolymer [, Xanthakos SA. The main role of carbohydrates is to provide energy for the body, especially the brain and nervous system. Ethnic differences in grains consumption and their contribution to intake of B-vitamins: results of the Multiethnic Cohort Study. However, talking with a healthcare provider about dietary supplements is important for those who live with the condition. J Nutr Metab. Cochrane Database Syst Rev 2013;7:CD004033. [, Carpenter KJ. A thiamine deficiency can become serious, so its important for those who might lack it to be tested and receive a supplement. A focused review, Potential thiamine deficiency in elderly patients with gastrointestinal cancer undergoing chemotherapy, Allithiamine exerts therapeutic effects on sepsis by modulating metabolic flux during dendritic cell activation, Therapeutic potential of vitamin B1 derivative benfotiamine from diabetes to COVID-19, Comparative pharmacokinetic analysis of thiamine and its phosphorylated metabolites administered as multivitamin preparations, Therapeutic benefits of an oral vitamin B1 derivative for human T lymphotropic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), Role of the synthetic B1 vitamin sulbutiamine on health, People with human immunodeficiency virus (HIV)/AIDS, Short-term memory loss or other mental problems, Numbness or tingling in the fingers or feet (, Confusion (temporospatial disorientation), Feeling of tingling or pins and needles in the extremities (, 1418 years: Males1.2 mg; females1.0 mg, 1950 years: Males1.2 mg; females1.1 mg, 51 years and over: Males1.2 mg; females1.1 mg, Allithiamine (thiamine allyl disulfide or TAD), Benfotiamine (S-benzoylthiamine-O-monophosphate), Fursultiamine (thiamine tetrahydrofurfuryl disulfide or TTFD), sold under the brand names Alinamin-F, Benlipoid, Bevitol Lipophil, Judolor, and Lipothiamine, Prosultiamine (thiamine propyl disulfide or TPD), including the brandJubedel, Sulbutiamine, sold under the brands Arcalion and Enerion. Mol Cell Neurosci 2013;55:17-25. Autopsies of 380 people with AIDS found that almost 10% had Wernickes encephalopathy [29], and some experts believe that thiamin deficiency is underdiagnosed in this population [30]. This vitamin plays a critical role in energy metabolism and, therefore, in the growth, development, and function of cells [1]. Food Labeling: Revision of the Nutrition and Supplement Facts Labels. Thiamine is vitamin B1, of which there are several different types that are used as supplements. When thiamine levels get too low, it may initially cause signs and symptoms such as: A more severe or long-term thiamine deficiency may cause complications, including conditions called beriberi and Wernicke-Korsakoff syndrome. Thiamin fact sheet for health professionals. There are many whole-food and fortified-food sources of thiamine, including: Thiamine (vitamin B1) is often found in multivitamins, usually with other B vitamins. However, even if supplements are third-party tested, it doesnt mean they are necessarily safe for all or effective in general. The body excretes excess amounts of thiamin in the urine [2]. How Do I Know If I Have a Thiamine Deficiency? [, Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Food sources of thiamin include whole grains, meat, and fish [2]. [, Wilkinson TJ, Hanger HC, George PM, Sainsbury R. Is thiamine deficiency in elderly people related to age or co-morbidity? [. [, Saito N, Kimura M, Kuchiba A, Itokawa Y. Thank you for your time. Other health problems, such as diabetes, may worsen the condition. However, as with any supplement, its still important to check with a healthcare provider on an appropriate dosage. Other studies have shown a higher risk of thiamin deficiency in people with type 1 and/or type 2 diabetes based on tests of erythrocyte transketolase activity [33,34]. Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. Overview. Elizabeth Barnes, RDN, is a registered dietitian nutritionist who specializes in eating disorders, type 2 diabetes, and heart health. Although thiamin is not known to interact with any medications, certain medications can have an adverse effect on thiamin levels. [, Alaei Shahmiri F, Soares MJ, Zhao Y, Sherriff J. High-dose thiamine supplementation improves glucose tolerance in hyperglycemic individuals: a randomized, double-blind cross-over trial. Reduced activities of thiamine-dependent enzymes in the brains and peripheral tissues of patients with Alzheimer's disease. By Amber J. Tresca Sci Prog. Autopsy studies have shown that transketolase and other thiamin-dependent enzymes have decreased activity in the brains of people with Alzheimers disease [52,53]. Vitamin B6, also calledPyridoxine hydrochloride, is one of 8 B vitamins. doi:10.7759/cureus.8027, Beltramo E, Mazzeo A, Porta M. Thiamine and diabetes: back to the future? Nutr Clin Pract. For people with diabetes who start to develop kidney damage (nephropathy), thiamine supplementation might be recommended. Some other forms of thiamine or vitamin B1, or derivatives, include: The level of the active form of thiamine (thiamine diphosphate) in whole blood is tested to determine a deficiency. Thiamine supplementation for the treatment of heart failure: a review of the literature. 2019;148:101-168. doi:10.1016/bs.irn.2019.09.002, Wang SC, Chen YC, Chen SJ, Lee CH, Cheng CM. A pilot study. Organs. What Happens If I Take Too Much Thiamine? US national trends in bariatric surgery: A decade of study. I AM IN LOVE WITH A CHRISTIAN GIRL CAN I MARRY HER? J Endocrinol Invest 2012;35:951-6. DRI is the general term for a set of reference values used for planning and assessing nutrient intakes of healthy people. Benefits. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. 2nd ed. Nicotinic Acid is a white crystalline powder with a molecular weight of 123.11. The fact that a vitamin source is indicated to be of synthetic origin does not guarantee that the tablet, capsule or liquid formula is Halal. Updated: Nolan KA, Black RS, Sheu KF, Langberg J, Blass JP. Eur Heart J. Am J Clin Nutr. Legumes and nuts like peanuts, cashew nuts, hazel nuts, walnuts, etc. Exp Ther Med. The proportion of people with type 1 or type 2 diabetes who have poor thiamin status based on erythrocyte transketolase activity ranges from 17% to 79% in studies conducted to date [40]. Hi do you guys have info on these: Cochrane Database Syst Rev. Ingested thiamin from food and dietary supplements is absorbed by the small intestine through active transport at nutritional doses and by passive diffusion at pharmacologic doses [1]. More research is needed to determine whether thiamin supplements might benefit people with heart failure, even if they have normal thiamin status. Hi, i just want to know about niacin and thiamin. [, Al-Attas OS, Al-Daghri NM, Alfadda AA, Abd-Alrahman SH, Sabico S. Blood thiamine and its phosphate esters as measured by high-performance liquid chromatography: levels and associations in diabetes mellitus patients with varying degrees of microalbuminuria. Join the ODS Email List. [. Thomson AD, Guerrini I, Marshall EJ. The discovery of thiamin. You may do the same if you notice an error in our list or want to know why the particular ingredient is halal, haram or doubtful. It is also not stored by the body, so a steady supply is needed. * Wernicke-Korsakoff syndrome is one of the most severe neuropsychiatric sequelae of alcohol abuse [37]. 2020;2020:9349063. doi:10.1155/2020/9349063. Alcohol Alcohol 2002;37:513-21. citrus fruit, tomatoes, etc). Thiamine is used to treat or prevent vitamin B1 deficiency. As many as 30% of people who have surgery on the upper digestive tract have some level of thiamine deficiency. [, Howard AJ, Kulkarni O, Lekwuwa G, Emsley HC. Most people who eat a normal diet do not need extra. Cognitive impairment severity in relation to signs of subclinical Wernicke's encephalopathy in HIV and alcoholism comorbidity. Is this your first time visiting our site? One cup (237 mL) beans or oats contains 1.8 or 1.2 mg thiamin, respectively. Thiamine injection is used to treat beriberi, a serious condition caused by prolonged lack of vitamin B1. Hashimoto's Disease-Related Fatigue and Thiamine Levels, Beriberi as a Result of Thiamine (Vitamin B1) Deficiency, Taking on Vitamin Deficiencies in Hepatitis C, Guide to Dietary Supplements and Thyroid Disease. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), which the body uses to produce energy. Explanations for this association include older age, comorbidities, insufficient dietary intake, treatment with diuretics, and frequent hospitalizations [48]. For infants from birth to 12 months, the FNB established an AI for thiamin that is equivalent to the mean intake of thiamin in healthy, breastfed infants. According to animal model studies, thiamin deficiency might play a role in the development of Alzheimers disease [51]. Some occur naturally in foods but might also be made synthetically in a lab. [. It is Halal if it is made from plant sources or if it is Halal or Kosher certified. 2018;1430(1):3-43. doi:10.1111/nyas.13919, Nunes PT, Kipp BT, Reitz NL, Savage LM. Maybe. Future Med Chem. In: Coates PM, Betz JM, Blackman MR, et al., eds. They then compared those who received the thiamine and those who didn't. Plants which are not intoxicant. Tolerable Upper Intake Level (UL): Maximum daily intake unlikely to cause adverse health effects. Vitamin D: Natural sources are yeast and fish liver oil. Kondo K, Fujiwara M, Murase M, Kodera Y, Akiyama S, Ito K, et al. Keith M, Quach S, Ahmed M, et al. Up to 20%30% of older adults have laboratory indicators that suggest some degree of thiamin deficiency [2,7]. The U.S. Department of Agricultures (USDAs) FoodData Central website [10] lists the nutrient content of many foods and provides a comprehensive list of foods containing thiamin arranged by nutrient content and by food name. J Nutr 2011;141:1847-54. In many patients, Wernicke-Korsakoff syndrome has two phases. Halal and Haram Ingredient Database. Antioxid Redox Signal 2007;9:1605-19. Xu M, Ji J, Lu Q, Gong J, Luo Z, Zhu L. The effects of thiamine supplementation on patients with heart failure: a systematic review and meta-analysis of randomized controlled trials. However, there is some evidence that the drugsLasix (furosemide) and Adrucil (fluorouracil)could cause the body to lose too much thiamine. Thiamine and diabetes: back to the future? Multivitamin/multimineral supplements with thiamin typically provide about 1.5 mg thiamin and sometimes more [12]. 2013;10(4):26-32. It is always mentioned along with Haraam which means sinful or prohibited by Allah. Washington, DC: National Academy Press; 1998. Includes a variety of vegetables; fruits; grains (at least half whole grains); fat-free and low-fat milk, yogurt, and cheese; and oils. The Royal College of Physicians report on alcohol: guidelines for managing Wernicke's encephalopathy in the accident and Emergency Department. Modern Nutrition in Health and Disease. People with HIV infection have an increased risk of thiamin deficiency and its sequelae, including beriberi and Wernicke-Korsakoff syndrome [1,28]. [, Day E, Bentham PW, Callaghan R, Kuruvilla T, George S. Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol. Thiamin is a water-soluble vitamin which is essential for energy metabolism. Data on the bioavailability of thiamin from food are very limited [7]. A focused review. Cancer Genomics Proteomics 2013;10:169-85. Larger, well-designed studies are needed to determine whether thiamin supplements are beneficial for Alzheimers disease. Here is a comprehensive list of halal and haram ingredients. FDA does not require food labels to list thiamin content unless thiamin has been added to the food. Most people get enough thiamine in their food. Thiamine is obtained from the diet. A case of Wernicke's encephalopathy following fluorouracil-based chemotherapy. National Institutes of Health Office of Dietary Supplements. Other vitamins and supplements may also be used as a treatment because other deficiencies might also be present. 2016;129:753.e7-753.e11. It can also be taken as a supplement on its own, in capsule or liquid form. Factors that can increase incidence include: Beriberi is a condition caused by low levels of thiamine. Alcohol Alcohol 2006;41:151-8. Apple Cider Vinegar (Halal in USA and Canada, verify in other countries), Artificial Colors or FD&C Yellow No. Can J Clin Pharmacol 2003;10:184-8. Taken orally, it's not expected to cause adverse reactions at higher levels, but theres also no data to prove otherwise. I do have a question about carrageenan your list says doubtful, However, the website of the International Food Ingredients council says this: A: Carrageenan is a vegan, plant-based ingredient that is essential to many vegetarian, vegan, halal, kosher, and organic food options. In rare cases, beriberi causes congestive heart failure that leads to edema in the lower limbs and, occasionally, death [1,3]. 2012;101:159-64. doi:10.1007/s00392-011-0376-2, Wong EKC, Lee JY, Chow J, et al. Wooley JA. Memiliki sertifikat halal dengan nomor 228820095002 yang berlaku sampai dengan 23 Oktober 2022 17 . For that reason, a deficiency may lead to a lack of certain enzymes. This disorder is about 810 times more common in people with chronic alcoholism than in the general population, but it can also develop in patients who have severe gastrointestinal disorders, rapidly progressing hematologic malignancies, drug use disorders, or AIDS [2]. It is also associated with HIV/AIDS, drug dependency, digestive diseases, and certain types of blood cancer. Vitamin B1: As Thiamine:Ingredients from plant or animal sources. B-Complex vitamins, including Vitamin B1, work to support energy metabolism in the body. Page GL, Laight D, Cummings MH. Three studies found that, compared to placebo, 120900 mg/day benfotiamine with or without other B-vitamins decreased the severity of neuropathy symptoms and lowered urinary albumin excretion (a marker of early-stage diabetic nephropathy) [43-45]. Thiamine (vitamin B1) is found in many foods and is used to treat low thiamine, beriberi, certain nerve diseases, and Wernicke-Korsakoff syndrome (WKS).
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